InnateDB Protein
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IDBP-163480.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cd226
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Protein Name
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CD226 antigen
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000043551
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InnateDB Gene
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IDBG-163478 (Cd226)
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Protein Structure
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Function |
Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
GO:0001816
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cytokine production
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GO:0002860
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positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
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GO:0002891
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positive regulation of immunoglobulin mediated immune response
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GO:0007155
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cell adhesion
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GO:0033005
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positive regulation of mast cell activation
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GO:0045954
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positive regulation of natural killer cell mediated cytotoxicity
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GO:0060369
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positive regulation of Fc receptor mediated stimulatory signaling pathway
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Cellular Component |
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PDB ID |
MGI:3039602
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InterPro |
IPR003599
Immunoglobulin subtype
IPR007110
Immunoglobulin-like domain
IPR013106
Immunoglobulin V-set domain
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PFAM |
PF07686
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PRINTS |
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PIRSF |
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SMART |
SM00409
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K4F0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q8K4E2
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UniProt Splice Variant |
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Entrez Gene |
225825
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UniGene |
Mm.139293
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RefSeq |
NP_848802
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MGI ID |
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MGI Symbol |
Cd226
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OMIM |
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CCDS |
CCDS29392
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HPRD |
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IMGT |
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EMBL |
AB195429
AF416980
AF421200
AK140349
BC132422
BC138769
CH466632
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GenPept |
AAI32423
AAI38770
AAN04295
AAN04298
BAD90660
BAE24349
EDL00649
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