InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lsm4

Summary

InnateDB Protein

IDBP-163814.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lsm4

Protein Name

LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034311

InnateDB Gene

IDBG-163812 (Lsm4)

Protein Structure

UniProt Annotation

Function

Binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	41 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0008150	biological_process
GO:0008380	RNA splicing

Cellular Component

GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1354692

InterPro

IPR001163 Ribonucleoprotein LSM domain
IPR006649 Ribonucleoprotein LSM domain, eukaryotic/archaea-type
IPR010920 Like-Sm (LSM) domain

PFAM

PF01423

PRINTS

PIRSF

SMART

SM00651

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9QXA5

PhosphoSite

PhosphoSite-

TrEMBL

Q9CY46

UniProt Splice Variant

Entrez Gene

50783

UniGene

RefSeq

NP_056631

MGI ID

MGI Symbol

Lsm4

OMIM

CCDS

CCDS40374

HPRD

IMGT

EMBL

AC162446 AC166931 AJ249439 AK010910 AK089028 AK143470 AK167784 BC026747 CH466569

GenPept

AAH26747 BAB27261 BAC40708 BAE25390 BAE39816 CAB65729 EDL28857