Version 5.4
Mus musculus Protein: Cep110
Summary
InnateDB Protein IDBP-164020.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep110
Protein Name centrosomal protein 110
Synonyms 6720467O09Rik; AA968343; b2b1468Clo; Cep1; Cep110; IB3/5; Ma2a8;
Species Mus musculus
Ensembl Protein ENSMUSP00000028237
InnateDB Gene IDBG-164016 (Cep110)
Protein Structure
UniProt Annotation
Function Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle- mediated abscission (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=During cytokinesis, localizes to a ring-like structure at the central midbody. {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in liver. {ECO:0000269PubMed:10688839}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007021 tubulin complex assembly
GO:0008150 biological_process
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005874 microtubule
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1889576
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR004226 Tubulin binding cofactor A
IPR010978 tRNA-binding arm
PFAM PF00560
PF13504
PF13855
PF02970
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AL36
PhosphoSite PhosphoSite-A2AL36
TrEMBL R4GML6
UniProt Splice Variant
Entrez Gene 26920
UniGene Mm.231332
RefSeq NP_036148
MGI ID
MGI Symbol Cntrl
OMIM
CCDS
HPRD
IMGT
EMBL AK020148 AK031338 AK041715 AK131139 AL773523 AL845534 BC038386
GenPept AAH38386 BAB32012 BAC27353 BAC31039 BAD21389 CAM16866 CAM16867 CAM16870 CAM17903 CAM17904 CAM17906 CAM17908

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca