Version 5.4
Mus musculus Gene: Cep110
Summary
InnateDB Gene IDBG-164016.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep110
Gene Name centrosomal protein 110
Synonyms 6720467O09Rik; AA968343; b2b1468Clo; Cep1; Cep110; IB3/5; Ma2a8
Species Mus musculus
Ensembl Gene ENSMUSG00000057110
Encoded Proteins
IDBP-164018
centrosomal protein 110
IDBP-164020
centrosomal protein 110
IDBP-254706
centrosomal protein 110
IDBP-254708
centrosomal protein 110
IDBP-254710
centrosomal protein 110
IDBP-254712
centrosomal protein 110
IDBP-538187
centrosomal protein 110
IDBP-541919
centrosomal protein 110
IDBP-532967
centrosomal protein 110
IDBP-535634
centrosomal protein 110
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119397:
This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:35109492-35178822
Strand Forward strand
Band B
Transcripts
ENSMUST00000028235 ENSMUSP00000028235
ENSMUST00000028237 ENSMUSP00000028237
ENSMUST00000113037 ENSMUSP00000108660
ENSMUST00000113034 ENSMUSP00000108657
ENSMUST00000113033 ENSMUSP00000108656
ENSMUST00000113032 ENSMUSP00000108655
ENSMUST00000156933 ENSMUSP00000118731
ENSMUST00000123884 ENSMUSP00000119760
ENSMUST00000150807
ENSMUST00000142757 ENSMUSP00000123300
ENSMUST00000136047 ENSMUSP00000123185
ENSMUST00000124081
ENSMUST00000137129
ENSMUST00000154214
ENSMUST00000130457
ENSMUST00000133209
ENSMUST00000143647
ENSMUST00000143807
ENSMUST00000138982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007021 tubulin complex assembly
GO:0008150 biological_process
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005874 microtubule
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119397
View Gene Order
ENSBTAG00000011417
Not yet available
Pathways
NETPATH
REACTOME
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_189085
Disease pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188177
Signaling by FGFR in disease pathway
REACT_188804
Cell Cycle pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_196455
Signaling by FGFR mutants pathway
REACT_196452
Signaling by FGFR1 mutants pathway
REACT_196460
Signaling by FGFR1 fusion mutants pathway
REACT_253753
Centrosome maturation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL R4GML6
UniProt Splice Variant
Entrez Gene 26920
UniGene Mm.231332
RefSeq XM_006498071 XM_006498076 NM_001290635 NM_012018 NM_030000 XM_006498068 XM_006498069 XM_006498070 XM_006498072 XM_006498073 XM_006498074 XM_006498075
OMIM
CCDS CCDS57170
HPRD
IMGT
MGI ID MGI:1889576
MGI Symbol Cntrl
EMBL AL773523 AL845534
GenPept
RNA Seq Atlas 26920

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca