InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ech1

Summary

InnateDB Protein

IDBP-164688.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ech1

Protein Name

enoyl coenzyme A hydratase 1, peroxisomal

Synonyms

AA617331;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000066092

InnateDB Gene

IDBG-164686 (Ech1)

Protein Structure

UniProt Annotation

Function

Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}. Peroxisome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0016853	isomerase activity

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005777	peroxisome
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1858208

InterPro

IPR001753 Crotonase superfamily
IPR029045 ClpP/crotonase-like domain

PFAM

PF00378

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O35459

PhosphoSite

PhosphoSite-O35459

TrEMBL

UniProt Splice Variant

Entrez Gene

51798

UniGene

RefSeq

NP_058052

MGI ID

MGI Symbol

Ech1

OMIM

CCDS

CCDS21057

HPRD

IMGT

EMBL

AF030343 BC068112 BC087924

GenPept

AAB84224 AAH68112 AAH87924