Version 5.4
Mus musculus Protein: Slc5a5
Summary
InnateDB Protein IDBP-164709.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc5a5
Protein Name solute carrier family 5 (sodium iodide symporter), member 5
Synonyms NIS;
Species Mus musculus
Ensembl Protein ENSMUSP00000000809
InnateDB Gene IDBG-164707 (Slc5a5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008507 sodium:iodide symporter activity
GO:0015111 iodide transmembrane transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0015705 iodide transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071320 cellular response to cAMP
GO:0071371 cellular response to gonadotropin stimulus
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2149330
InterPro IPR001734 Sodium/solute symporter
IPR019900 Sodium/solute symporter, subgroup
PFAM PF00474
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3X8P5
UniProt Splice Variant
Entrez Gene 114479
UniGene Mm.172923
RefSeq NP_444478
MGI ID
MGI Symbol Slc5a5
OMIM
CCDS CCDS22385
HPRD
IMGT
EMBL AC019302 CH466569
GenPept EDL28884

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca