InnateDB Protein
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IDBP-164857.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Lsm11
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Protein Name
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U7 snRNP-specific Sm-like protein LSM11
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Synonyms
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2210404M20Rik; AV079530;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000057343
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InnateDB Gene
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IDBG-164855 (Lsm11)
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Protein Structure
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Function |
Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA. {ECO:0000269PubMed:12975319, ECO:0000269PubMed:15824063, ECO:0000269PubMed:16914750}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1919540
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InterPro |
IPR001163
Ribonucleoprotein LSM domain
IPR006649
Ribonucleoprotein LSM domain, eukaryotic/archaea-type
IPR010920
Like-Sm (LSM) domain
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PFAM |
PF01423
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PRINTS |
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PIRSF |
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SMART |
SM00651
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BUV6
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PhosphoSite |
PhosphoSite-Q8BUV6
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TrEMBL |
Q9CVB3
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UniProt Splice Variant |
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Entrez Gene |
72290
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UniGene |
Mm.455600
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RefSeq |
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MGI ID |
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MGI Symbol |
Lsm11
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OMIM |
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CCDS |
CCDS36131
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HPRD |
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IMGT |
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EMBL |
AF514309
AK008830
AK082292
AK143661
BC094286
CH466575
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GenPept |
AAH94286
AAQ08118
BAB25917
BAC38456
BAE25483
EDL33832
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