InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tm2d1

Summary

InnateDB Protein

IDBP-165038.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tm2d1

Protein Name

TM2 domain containing 1

Synonyms

2310026L18Rik; AA990549; Bbp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099855

InnateDB Gene

IDBG-165036 (Tm2d1)

Protein Structure

UniProt Annotation

Function

May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001540	beta-amyloid binding
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0097190	apoptotic signaling pathway

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

MGI:2137022

InterPro

IPR007829 TM2

PFAM

PF05154

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99MB3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

94043

UniGene

RefSeq

NP_444387

MGI ID

MGI Symbol

Tm2d1

OMIM

CCDS

CCDS18374

HPRD

IMGT

EMBL

AF353993 AK009511 AL671140 BC089492

GenPept

AAH89492 AAK35067 CAM26981 CAM26983 CAM26984