Mus musculus Protein: Dock7
Summary
InnateDB Protein IDBP-165731.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Dock7
Protein Name dedicator of cytokinesis 7
Synonyms 3110056M06Rik; Gm430; m;
Species Mus musculus
Ensembl Protein ENSMUSP00000075233
InnateDB Gene IDBG-165723 (Dock7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0048365 Rac GTPase binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0002244 hematopoietic progenitor cell differentiation
GO:0007264 small GTPase mediated signal transduction
GO:0007409 axonogenesis
GO:0032863 activation of Rac GTPase activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043473 pigmentation
GO:0045200 establishment of neuroblast polarity
Cellular Component
GO:0008180 COP9 signalosome
Protein Structure and Domains
PDB ID MGI:1914549
InterPro IPR010703 Dedicator of cytokinesis C-terminal
IPR016024 Armadillo-type fold
IPR021816 Dedicator of cytokinesis C/D, N-terminal
PFAM PF06920
PF11878
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-NP_080358
TrEMBL Q7TPP0
UniProt Splice Variant
Entrez Gene 67299
UniGene Mm.260623
RefSeq NP_080358
MGI ID
MGI Symbol Dock7
OMIM
CCDS CCDS38816
HPRD
IMGT
EMBL AL627349 AL627393 AL935325 BC055032
GenPept AAH55032