InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tnp1

Summary

InnateDB Protein

IDBP-166223.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tnp1

Protein Name

transition protein 1

Synonyms

Stp-1; Tp-1; TP1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027374

InnateDB Gene

IDBG-166221 (Tnp1)

Protein Structure

UniProt Annotation

Function

In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.

Subcellular Localization

Nucleus. Chromosome.

Disease Associations

Tissue Specificity

Testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding

Biological Process

GO:0000012	single strand break repair
GO:0006337	nucleosome disassembly
GO:0006338	chromatin remodeling
GO:0006342	chromatin silencing
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0007286	spermatid development
GO:0007290	spermatid nucleus elongation
GO:0019953	sexual reproduction
GO:0030317	sperm motility
GO:0045892	negative regulation of transcription, DNA-templated