Version 5.4
Mus musculus Gene: Tnp1
Summary
InnateDB Gene IDBG-166221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnp1
Gene Name transition protein 1
Synonyms Stp-1; Tp-1; TP1
Species Mus musculus
Ensembl Gene ENSMUSG00000026182
Encoded Proteins
IDBP-166223
transition protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118245:
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:73015074-73015909
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000027374 ENSMUSP00000027374
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0000012 single strand break repair
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0006342 chromatin silencing
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0007290 spermatid nucleus elongation
GO:0019953 sexual reproduction
GO:0030317 sperm motility
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0000786 nucleosome
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000118245
View Gene Order
ENSBTAG00000019003
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_009407
OMIM
CCDS CCDS35611
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca