Version 5.4
Mus musculus Protein: Frat2
Summary
InnateDB Protein IDBP-166309.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Frat2
Protein Name frequently rearranged in advanced T-cell lymphomas 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000052788
InnateDB Gene IDBG-166307 (Frat2)
Protein Structure
UniProt Annotation
Function Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0016055 Wnt signaling pathway
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2673967
InterPro IPR008014 Glycogen synthase kinase-3 binding protein
PFAM PF05350
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K025
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 212398
UniGene Mm.222723
RefSeq NP_808271
MGI ID
MGI Symbol Frat2
OMIM
CCDS CCDS29813
HPRD
IMGT
EMBL AK081171 AY518895 BC034214 BC085510
GenPept AAH34214 AAH85510 AAR99812 BAC38155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca