InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pgm2

Summary

InnateDB Protein

IDBP-166729.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pgm2

Protein Name

phosphoglucomutase 2

Synonyms

2610020G18Rik; AA407108; AI098105; Pgm-2; Pgm1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000061227

InnateDB Gene

IDBG-166725 (Pgm2)

Protein Structure

UniProt Annotation

Function

This enzyme participates in both the breakdown and synthesis of glucose. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004614	phosphoglucomutase activity
GO:0016868	intramolecular transferase activity, phosphotransferases

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0005978	glycogen biosynthetic process
GO:0006006	glucose metabolic process
GO:0019388	galactose catabolic process

Cellular Component

GO:0005829	cytosol
GO:0015629	actin cytoskeleton
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:97565

InterPro

IPR005841 Alpha-D-phosphohexomutase superfamily
IPR005843 Alpha-D-phosphohexomutase, C-terminal
IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III
IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

PFAM

PF00408
PF02878
PF02879
PF02880

PRINTS

PR00509

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D0F9