InnateDB Protein
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IDBP-167582.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hnrnpm
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Protein Name
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heterogeneous nuclear ribonucleoprotein M
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Synonyms
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2610023M21Rik; AA409009; Hnrpm; mKIAA4193;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000084864
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InnateDB Gene
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IDBG-167580 (Hnrnpm)
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Protein Structure
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Function |
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 181 interaction(s) predicted by orthology.
Experimentally validated |
Total |
23
[view]
|
Protein-Protein |
22
[view]
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
181 [view]
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|
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Molecular Function |
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Biological Process |
GO:0000380
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alternative mRNA splicing, via spliceosome
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Cellular Component |
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PDB ID |
MGI:1926465
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InterPro |
IPR000504
RNA recognition motif domain
IPR024666
Heterogeneous nuclear ribonucleoprotein M, PY nuclear localisation signal
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PFAM |
PF00076
PF11532
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D0E1
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PhosphoSite |
PhosphoSite-Q9D0E1
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TrEMBL |
Q570Z0
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UniProt Splice Variant |
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Entrez Gene |
76936
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UniGene |
Mm.399541
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RefSeq |
NP_001103383
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MGI ID |
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MGI Symbol |
Hnrnpm
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OMIM |
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CCDS |
CCDS50068
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HPRD |
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IMGT |
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EMBL |
AK011521
AK145343
AK163866
AK168347
AK171892
AK220299
BC005758
BC065172
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GenPept |
AAH05758
AAH65172
BAB27675
BAD90224
BAE26377
BAE37519
BAE40284
BAE42723
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