InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp8a1

Summary

InnateDB Protein

IDBP-168127.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Atp8a1

Protein Name

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

Synonyms

AI481521; AI853962; APLT; Atp3a2; AW743152; AW822227; B230107D19Rik; ClassI;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000042215

InnateDB Gene

IDBG-168125 (Atp8a1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding

Biological Process

GO:0006812	cation transport
GO:0008152	metabolic process
GO:0015914	phospholipid transport
GO:0045332	phospholipid translocation

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1330848

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR006539 Cation-transporting P-type ATPase, subfamily IV
IPR008250 P-type ATPase, A domain
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM

PF00122
PF00702
PF08282
PF13419

PRINTS

PR00119
PR00120

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite