Version 5.4
Mus musculus Gene: Atp8a1
Summary
InnateDB Gene IDBG-168125.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp8a1
Gene Name ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Synonyms AI481521; AI853962; APLT; Atp3a2; AW743152; AW822227; B230107D19Rik; ClassI
Species Mus musculus
Ensembl Gene ENSMUSG00000037685
Encoded Proteins
IDBP-168127
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
IDBP-168129
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
IDBP-253388
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
IDBP-253390
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
IDBP-534418
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
IDBP-540679
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124406:
The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:67618140-67847432
Strand Reverse strand
Band C3.1
Transcripts
ENSMUST00000037380 ENSMUSP00000042215
ENSMUST00000072971 ENSMUSP00000072738
ENSMUST00000113652 ENSMUSP00000109282
ENSMUST00000113651 ENSMUSP00000109281
ENSMUST00000135930 ENSMUSP00000118379
ENSMUST00000149501
ENSMUST00000155911
ENSMUST00000152433
ENSMUST00000130652
ENSMUST00000143013
ENSMUST00000128726
ENSMUST00000141443 ENSMUSP00000121630
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 cation transport
GO:0007612 learning
GO:0008152 metabolic process
GO:0015914 phospholipid transport
GO:0030335 positive regulation of cell migration
GO:0045332 phospholipid translocation
GO:0061092 positive regulation of phospholipid translocation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042584 chromaffin granule membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124406
View Gene Order
ENSBTAG00000011156
Not yet available
Pathways
NETPATH
REACTOME
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_250224
Ion transport by P-type ATPases pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.153230 Mm.440990 Mm.479216
RefSeq NM_001038999 NM_001284345 NM_009727 XM_006503699 XM_006503702 XM_006503704 XM_006503705
OMIM
CCDS CCDS39104 CCDS39105
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca