InnateDB Protein
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IDBP-168871.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Agpat3
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Protein Name
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1-acylglycerol-3-phosphate O-acyltransferase 3
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Synonyms
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AW061257; AW493985; D10Jhu12e; lpaat3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000001240
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InnateDB Gene
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IDBG-168869 (Agpat3)
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Protein Structure
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Function |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. {ECO:0000269PubMed:15367102}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Nucleus envelope {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. {ECO:0000269PubMed:15367102}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003841
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1-acylglycerol-3-phosphate O-acyltransferase activity
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GO:0016746
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transferase activity, transferring acyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1336186
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InterPro |
IPR002123
Phospholipid/glycerol acyltransferase
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PFAM |
PF01553
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PRINTS |
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PIRSF |
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SMART |
SM00563
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D517
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PhosphoSite |
PhosphoSite-Q9D517
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TrEMBL |
D3Z1M6
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UniProt Splice Variant |
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Entrez Gene |
28169
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UniGene |
Mm.487872
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RefSeq |
XP_006513779
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MGI ID |
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MGI Symbol |
Agpat3
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OMIM |
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CCDS |
CCDS23963
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HPRD |
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IMGT |
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EMBL |
AB377215
AC160405
AC160411
AK015906
AK030607
AK075715
AK076414
AY167588
BC052382
BC058519
CH466553
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GenPept |
AAH52382
AAH58519
AAN75574
BAB30025
BAC27043
BAC35905
BAC36329
BAH59614
EDL31738
EDL31739
EDL31740
EDL31742
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