Version 5.4
Mus musculus Gene: Agpat3
Summary
InnateDB Gene IDBG-168869.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agpat3
Gene Name 1-acylglycerol-3-phosphate O-acyltransferase 3
Synonyms AW061257; AW493985; D10Jhu12e; lpaat3
Species Mus musculus
Ensembl Gene ENSMUSG00000001211
Encoded Proteins
IDBP-168871
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-270980
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-270982
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-270984
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-270986
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-532402
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-541667
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-537014
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-534607
1-acylglycerol-3-phosphate O-acyltransferase 3
IDBP-627809
1-acylglycerol-3-phosphate O-acyltransferase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160216:
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:78269178-78352489
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000001240 ENSMUSP00000001240
ENSMUST00000105390 ENSMUSP00000101029
ENSMUST00000105389 ENSMUSP00000101028
ENSMUST00000105388 ENSMUSP00000101027
ENSMUST00000105387 ENSMUSP00000101026
ENSMUST00000146296
ENSMUST00000139282 ENSMUSP00000119713
ENSMUST00000150828 ENSMUSP00000114885
ENSMUST00000138035 ENSMUSP00000121052
ENSMUST00000146899 ENSMUSP00000114657
ENSMUST00000166360 ENSMUSP00000132954
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0008152 metabolic process
GO:0016024 CDP-diacylglycerol biosynthetic process
Cellular Component
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160216
View Gene Order
ENSBTAG00000020456
Not yet available
Pathways
NETPATH
REACTOME
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_237947
Triglyceride Biosynthesis pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188640
Synthesis of PA pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu00564
Glycerophospholipid metabolism pathway
mmu00561
Glycerolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120906
Synthesis of PA pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9D517
TrEMBL C4B4E7 D3YTN7 D3YUW0 D3YV65 D3Z1M6
UniProt Splice Variant
Entrez Gene 28169
UniGene Mm.141230 Mm.408551 Mm.418597 Mm.487872
RefSeq XM_006513725 NM_053014 XM_006513716 XM_006513717 XM_006513718 XM_006513719 XM_006513720 XM_006513721 XM_006513722 XM_006513723 XM_006513724
OMIM
CCDS CCDS23963
HPRD
IMGT
MGI ID MGI:1336186
MGI Symbol Agpat3
EMBL AB377215 AC160405 AC160411 AK015906 AK030607 AK075715 AK076414 AY167588 BC052382 BC058519 CH466553
GenPept AAH52382 AAH58519 AAN75574 BAB30025 BAC27043 BAC35905 BAC36329 BAH59614 EDL31738 EDL31739 EDL31740 EDL31742
RNA Seq Atlas 28169

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca