Version 5.4
Mus musculus Protein: Nr3c2
Summary
InnateDB Protein IDBP-169160.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Nr3c2
Protein Name nuclear receptor subfamily 3, group C, member 2
Synonyms Mlr; MR;
Species Mus musculus
Ensembl Protein ENSMUSP00000034031
InnateDB Gene IDBG-169158 (Nr3c2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006883 cellular sodium ion homeostasis
GO:0007588 excretion
GO:0043401 steroid hormone mediated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID MGI:99459
InterPro IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR008946 Nuclear hormone receptor, ligand-binding
PFAM PF00104
PF00105
PRINTS PR00047
PIRSF
SMART SM00430
SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q8M8
UniProt Splice Variant
Entrez Gene 110784
UniGene Mm.397419
RefSeq
MGI ID
MGI Symbol Nr3c2
OMIM
CCDS
HPRD
IMGT
EMBL AC113941 AC116768 AC118019 AC119248
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca