InnateDB Protein
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IDBP-16976.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IL17RC
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Protein Name
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interleukin 17 receptor C
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000295981
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InnateDB Gene
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IDBG-16972 (IL17RC)
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Protein Structure
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Function |
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Subcellular Localization |
Cell membrane; Single-pass type I membrane protein. Note=Soluble isoforms may be produced.
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Disease Associations |
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Tissue Specificity |
Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta. {ECO:0000269PubMed:11706037}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
10
[view]
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Protein-Protein |
10
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
GO:0019221
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cytokine-mediated signaling pathway
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GO:1900017
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positive regulation of cytokine production involved in inflammatory response
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Cellular Component |
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PDB ID |
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InterPro |
IPR013568
SEFIR
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PFAM |
PF08357
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NAC3
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PhosphoSite |
PhosphoSite-Q8NAC3
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TrEMBL |
A0A024R2E7
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UniProt Splice Variant |
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Entrez Gene |
84818
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UniGene |
Hs.714274
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RefSeq |
NP_703191
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HUGO |
HGNC:18358
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OMIM |
610925
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CCDS |
CCDS2590
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HPRD |
17142
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IMGT |
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EMBL |
AC018809
AF458065
AK092907
AY358840
AY359098
BC006411
CH471055
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GenPept |
AAM77569
AAQ89199
AAQ89456
BAC04001
EAW64025
EAW64026
EAW64027
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