Version 5.4
Homo sapiens Protein: IL17RC
Summary
InnateDB Protein IDBP-16984.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL17RC
Protein Name interleukin 17 receptor C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000373323
InnateDB Gene IDBG-16972 (IL17RC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane; Single-pass type I membrane protein. Note=Soluble isoforms may be produced.
Disease Associations
Tissue Specificity Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta. {ECO:0000269PubMed:11706037}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030368 interleukin-17 receptor activity
Biological Process
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR013568 SEFIR
PFAM PF08357
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NAC3
PhosphoSite PhosphoSite-Q8NAC3
TrEMBL A0A024R2E7
UniProt Splice Variant
Entrez Gene 84818
UniGene Hs.714274
RefSeq NP_116121
HUGO HGNC:18358
OMIM 610925
CCDS CCDS2591
HPRD 17142
IMGT
EMBL AC018809 AF458065 AK092907 AY358840 AY359098 BC006411 CH471055
GenPept AAM77569 AAQ89199 AAQ89456 BAC04001 EAW64025 EAW64026 EAW64027

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca