InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cnga1

Summary

InnateDB Protein

IDBP-169986.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnga1

Protein Name

cyclic nucleotide gated channel alpha 1

Synonyms

Cncg;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000084464

InnateDB Gene

IDBG-169984 (Cnga1)

Protein Structure

UniProt Annotation

Function

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Rod cells in the retina and inner medulla of kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005222	intracellular cAMP activated cation channel activity
GO:0005223	intracellular cGMP activated cation channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding
GO:0030553	cGMP binding

Biological Process

GO:0006811	ion transport
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0042391	regulation of membrane potential
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport