InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cnga1

Summary

InnateDB Gene

IDBG-169984.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnga1

Gene Name

cyclic nucleotide gated channel alpha 1

Synonyms

Cncg

Species

Mus musculus

Ensembl Gene

ENSMUSG00000067220

Encoded Proteins

IDBP-169986

cyclic nucleotide gated channel alpha 1

IDBP-535190

cyclic nucleotide gated channel alpha 1

IDBP-628362

cyclic nucleotide gated channel alpha 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198515:
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:72603696-72642752

Strand

Reverse strand

Band

C3.2

Transcripts

ENSMUST00000087213	ENSMUSP00000084464
ENSMUST00000126799
ENSMUST00000135701	ENSMUSP00000119886
ENSMUST00000169997	ENSMUSP00000132329

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005222	intracellular cAMP activated cation channel activity
GO:0005223	intracellular cGMP activated cation channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding
GO:0030553	cGMP binding

Biological Process

GO:0006811	ion transport
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0042391	regulation of membrane potential
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport