InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Diap2

Summary

InnateDB Protein

IDBP-170057.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Diap2

Protein Name

diaphanous homolog 2 (Drosophila)

Synonyms

Dia3; Diaph2; Drf2; E430022I22Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039334

InnateDB Gene

IDBG-170053 (Diap2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005488	binding
GO:0017048	Rho GTPase binding

Biological Process

GO:0007292	female gamete generation
GO:0016043	cellular component organization
GO:0030036	actin cytoskeleton organization
GO:0030041	actin filament polymerization

Cellular Component

GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

MGI:1858500

InterPro

IPR010465 DRF autoregulatory
IPR010472 Formin, FH3 domain
IPR010473 Formin, GTPase-binding domain
IPR015425 Formin, FH2 domain
IPR016024 Armadillo-type fold

PFAM

PF06345
PF06367
PF06371
PF02181

PRINTS

PIRSF

SMART

SM00498

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite