InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: H2-Oa

Summary

InnateDB Protein

IDBP-170182.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

H2-Oa

Protein Name

histocompatibility 2, O region alpha locus

Synonyms

H-2Oa;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025192

InnateDB Gene

IDBG-170180 (H2-Oa)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0023026	MHC class II protein complex binding

Biological Process

GO:0002587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0006955	immune response
GO:0019882	antigen processing and presentation
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045580	regulation of T cell differentiation

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042613	MHC class II protein complex

Protein Structure and Domains

PDB ID

MGI:95924

InterPro

IPR001003 MHC class II, alpha chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein

PFAM

PF00993
PF07654

PRINTS

PIRSF

SMART

SM00920
SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite