InnateDB Protein
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IDBP-170289.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Setd3
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Protein Name
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SET domain containing 3
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Synonyms
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2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000066413
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InnateDB Gene
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IDBG-170285 (Setd3)
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Protein Structure
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Function |
Histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
Accession |
GO Term |
GO:0001102
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RNA polymerase II activating transcription factor binding
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GO:0003713
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transcription coactivator activity
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GO:0005515
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protein binding
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GO:0042800
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histone methyltransferase activity (H3-K4 specific)
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GO:0046975
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histone methyltransferase activity (H3-K36 specific)
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1289184
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InterPro |
IPR001214
SET domain
IPR015353
Rubisco LSMT, substrate-binding domain
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PFAM |
PF00856
PF09273
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PRINTS |
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PIRSF |
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SMART |
SM00317
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TIGRFAMs |
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Modification |
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SwissProt |
Q91WC0
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PhosphoSite |
PhosphoSite-Q91WC0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
52690
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UniGene |
Mm.472969
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RefSeq |
NP_082538
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MGI ID |
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MGI Symbol |
Setd3
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OMIM |
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CCDS |
CCDS26159
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HPRD |
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IMGT |
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EMBL |
AK011993
AK029403
AK031017
AK031371
AK146777
AK166570
AY513271
BC016123
BC019973
BC057968
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GenPept |
AAH16123
AAH19973
AAH57968
AAS82953
BAB27964
BAC26435
BAC27215
BAC27371
BAE27425
BAE38861
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