InnateDB Protein
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IDBP-170298.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dhcr24
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Protein Name
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24-dehydrocholesterol reductase
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Synonyms
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2310076D10Rik; 5830417J06Rik; mKIAA0018;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000038063
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InnateDB Gene
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IDBG-170296 (Dhcr24)
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Protein Structure
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Function |
Catalyzes the reduction of the delta-24 double bond of sterol intermediates. {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003824
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catalytic activity
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GO:0008762
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UDP-N-acetylmuramate dehydrogenase activity
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GO:0016491
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oxidoreductase activity
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GO:0016614
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oxidoreductase activity, acting on CH-OH group of donors
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GO:0016628
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oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
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GO:0019899
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enzyme binding
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GO:0042605
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peptide antigen binding
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GO:0050614
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delta24-sterol reductase activity
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GO:0050660
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flavin adenine dinucleotide binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1922004
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InterPro |
IPR006094
FAD linked oxidase, N-terminal
IPR016166
FAD-binding, type 2
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PFAM |
PF01565
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8VCH6
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PhosphoSite |
PhosphoSite-Q8VCH6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
74754
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UniGene |
Mm.411568
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RefSeq |
NP_444502
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MGI ID |
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MGI Symbol |
Dhcr24
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OMIM |
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CCDS |
CCDS18420
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HPRD |
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IMGT |
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EMBL |
AK017937
AK129036
AL929585
AY039762
BC019797
BX511043
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GenPept |
AAH19797
AAK72106
BAB31012
BAC97846
CAM27475
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