Version 5.4
Mus musculus Protein: Mpi
Summary
InnateDB Protein IDBP-170304.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mpi
Protein Name mannose phosphate isomerase
Synonyms 1110002E17Rik; AI315153; Mpi-1; Mpi1;
Species Mus musculus
Ensembl Protein ENSMUSP00000034856
InnateDB Gene IDBG-170302 (Mpi)
Protein Structure
UniProt Annotation
Function Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:12122025}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004476 mannose-6-phosphate isomerase activity
GO:0008270 zinc ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009298 GDP-mannose biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:97075
InterPro IPR001250 Mannose-6-phosphate isomerase, type I
IPR011051 RmlC-like cupin domain
IPR016305 Mannose-6-phosphate isomerase
PFAM PF01238
PRINTS PR00714
PIRSF PIRSF001480
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q924M7
PhosphoSite PhosphoSite-Q924M7
TrEMBL Q3V100
UniProt Splice Variant
Entrez Gene 110119
UniGene
RefSeq NP_080113
MGI ID
MGI Symbol Mpi
OMIM
CCDS CCDS40650
HPRD
IMGT
EMBL AF244360 AK132777 BC051163 CH466522
GenPept AAH51163 AAK69388 BAE21353 EDL25909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca