InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP8A2

Summary

InnateDB Protein

IDBP-17055.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP8A2

Protein Name

ATPase, aminophospholipid transporter, class I, type 8A, member 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000281620

InnateDB Gene

IDBG-17053 (ATP8A2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005524	ATP binding
GO:0046872	metal ion binding

Biological Process

GO:0015914	phospholipid transport
GO:0045332	phospholipid translocation

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006539 Cation-transporting P-type ATPase, subfamily IV
IPR008250 P-type ATPase, A domain
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM

PF00122
PF00702
PF08282
PF13419

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-