InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp4a

Summary

InnateDB Protein

IDBP-170934.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp4a

Protein Name

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000005692

InnateDB Gene

IDBG-170932 (Atp4a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0005524	ATP binding
GO:0008900	hydrogen:potassium-exchanging ATPase activity
GO:0015077	monovalent inorganic cation transmembrane transporter activity
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006754	ATP biosynthetic process
GO:0006812	cation transport
GO:0010155	regulation of proton transport
GO:0015672	monovalent inorganic cation transport
GO:0015991	ATP hydrolysis coupled proton transport
GO:0042493	response to drug
GO:0045851	pH reduction

Cellular Component

GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:88113

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR004014 Cation-transporting P-type ATPase, N-terminal
IPR005775 Sodium/potassium-transporting P-type ATPase, subfamily IIC
IPR006068 Cation-transporting P-type ATPase, C-terminal
IPR008250 P-type ATPase, A domain
IPR015127 Gastric H+/K+-transporter P-type ATPase, N-terminal
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM