InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Notch4

Summary

InnateDB Protein

IDBP-171822.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Notch4

Protein Name

Notch gene homolog 4 (Drosophila)

Synonyms

Int-3; Int3; N4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000015612

InnateDB Gene

IDBG-171820 (Notch4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001886	endothelial cell morphogenesis
GO:0007219	Notch signaling pathway
GO:0007275	multicellular organismal development
GO:0030154	cell differentiation
GO:0030879	mammary gland development
GO:0045446	endothelial cell differentiation
GO:0050793	regulation of developmental process

Cellular Component

GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:107471

InterPro

IPR000742 Epidermal growth factor-like domain
IPR000800 Notch domain
IPR001881 EGF-like calcium-binding domain
IPR002110 Ankyrin repeat
IPR008297 Notch
IPR011656 Notch, NODP domain
IPR020683 Ankyrin repeat-containing domain
IPR022355 Neurogenic locus Notch 4

PFAM