Version 5.4
Mus musculus Protein: Elmod2
Summary
InnateDB Protein IDBP-171887.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elmod2
Protein Name ELMO domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000052287
InnateDB Gene IDBG-171885 (Elmod2)
Protein Structure
UniProt Annotation
Function Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0006909 phagocytosis
GO:0043547 positive regulation of GTPase activity
GO:0050688 regulation of defense response to virus
Cellular Component
GO:0005575 cellular_component
GO:0005856 cytoskeleton
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:2445165
InterPro IPR006816 Engulfment/cell motility, ELMO
PFAM PF04727
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGF6
PhosphoSite PhosphoSite-Q8BGF6
TrEMBL Q8BHN8
UniProt Splice Variant
Entrez Gene 244548
UniGene Mm.409753
RefSeq XP_006531042
MGI ID
MGI Symbol Elmod2
OMIM
CCDS CCDS22450
HPRD
IMGT
EMBL AK029044 AK036746 AK041137 AK082730 AK084950 BC079654
GenPept AAH79654 BAC26262 BAC29561 BAC30834 BAC38591 BAC39319

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca