Version 5.4
| Mus musculus Gene: Elmod2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||
| InnateDB Gene | IDBG-171885.7 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Elmod2 | ||||||||||||
| Gene Name | ELMO/CED-12 domain containing 2 | ||||||||||||
| Synonyms | |||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Gene | ENSMUSG00000035151 | ||||||||||||
| Encoded Proteins |
ELMO domain containing 2
|
||||||||||||
| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| InnateDB Annotation from Orthologs | |||||||||||||
| Summary |
[Homo sapiens] ELMOD2 regulates the TLR3 signalling pathway where silencing of ELMOD2 in human macrophages inhibited TLR3-dependent expression of type I and type III interferon genes.
|
||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179387:
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010] |
||||||||||||
| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 8:83312632-83332486 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | C2 | ||||||||||||
| Transcripts |
|
||||||||||||
| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
|
||||||||||||
| Gene Ontology | |||||||||||||
Molecular Function |
|
||||||||||||
| Biological Process |
|
||||||||||||
| Cellular Component |
|
||||||||||||
| Orthologs | |||||||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | |||||||||||||
| UniGene | Mm.38762 Mm.409753 | ||||||||||||
| RefSeq | NM_001170691 NM_178736 XM_006530979 XM_006530980 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS22450 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| MGI ID | |||||||||||||
| MGI Symbol | |||||||||||||
| EMBL | |||||||||||||
| GenPept | |||||||||||||
| RNA Seq Atlas | |||||||||||||