InnateDB Protein
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IDBP-172316.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ctsb
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Protein Name
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cathepsin B
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Synonyms
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CB;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000006235
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InnateDB Gene
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IDBG-172314 (Ctsb)
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Protein Structure
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|
Function |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
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Subcellular Localization |
Lysosome. Melanosome {ECO:0000250}. Secreted, extracellular space {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
12
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
24 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:88561
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InterPro |
IPR000668
Peptidase C1A, papain C-terminal
IPR012599
Peptidase C1A, propeptide
|
PFAM |
PF00112
PF08127
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PRINTS |
PR00705
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PIRSF |
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SMART |
SM00645
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TIGRFAMs |
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Modification |
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SwissProt |
P10605
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PhosphoSite |
PhosphoSite-P10605
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
13030
|
UniGene |
Mm.488723
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RefSeq |
NP_031824
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MGI ID |
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MGI Symbol |
Ctsb
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OMIM |
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CCDS |
CCDS27197
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HPRD |
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IMGT |
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EMBL |
AK083393
AK147192
AK149884
AK151790
AK167361
BC006656
M14222
M65263
M65264
M65265
M65266
M65267
M65268
M65269
M65270
S69034
X54966
|
GenPept |
AAA37375
AAA37494
AAB20536
AAH06656
BAC38900
BAE27751
BAE29144
BAE30691
BAE39458
CAA38713
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