Version 5.4
Homo sapiens Protein: ZNF74
Summary
InnateDB Protein IDBP-1725.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF74
Protein Name zinc finger protein 74
Synonyms COS52; hZNF7; ZFP520; ZNF520;
Species Homo sapiens
Ensembl Protein ENSP00000349098
InnateDB Gene IDBG-1721 (ZNF74)
Protein Structure
UniProt Annotation
Function May play a role in RNA metabolism.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Highly expressed in the fetal brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003723 RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q16587
PhosphoSite PhosphoSite-Q16587
TrEMBL
UniProt Splice Variant
Entrez Gene 7625
UniGene Hs.517418
RefSeq NP_001243454
HUGO HGNC:13144
OMIM 194548
CCDS
HPRD 01928
IMGT
EMBL AC007731 AF072557 AF072562 AF072567 AK299569 BC013395 BC056902 CR456616 X63182 X71623 X92715
GenPept AAF21777 AAF21778 AAF21779 AAF21780 AAH13395 BAH13068 CAA50632 CAA63379 CAC16149 CAG30502

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca