InnateDB Protein
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IDBP-172964.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Acsl6
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Protein Name
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acyl-CoA synthetase long-chain family member 6
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000090795
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InnateDB Gene
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IDBG-172962 (Acsl6)
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Protein Structure
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Function |
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:894291
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InterPro |
IPR000873
AMP-dependent synthetase/ligase
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PFAM |
PF00501
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91WC3
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PhosphoSite |
PhosphoSite-Q91WC3
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TrEMBL |
Q5ICG4
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UniProt Splice Variant |
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Entrez Gene |
216739
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UniGene |
Mm.267478
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RefSeq |
NP_001028770
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MGI ID |
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MGI Symbol |
Acsl6
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OMIM |
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CCDS |
CCDS24696
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HPRD |
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IMGT |
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EMBL |
AK147283
AL596127
AL603822
AY167035
AY786363
BC016114
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GenPept |
AAH16114
AAO38689
AAW33886
BAE27819
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