InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dmgdh

Summary

InnateDB Protein

IDBP-173070.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dmgdh

Protein Name

dimethylglycine dehydrogenase precursor

Synonyms

1200014D15Rik; AI787269;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039663

InnateDB Gene

IDBG-173068 (Dmgdh)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004047	aminomethyltransferase activity
GO:0016491	oxidoreductase activity
GO:0044822	poly(A) RNA binding
GO:0047865	dimethylglycine dehydrogenase activity

Biological Process

GO:0006544	glycine metabolic process
GO:0006546	glycine catabolic process
GO:0006579	amino-acid betaine catabolic process
GO:0032259	methylation
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:1921379

InterPro

IPR006076 FAD dependent oxidoreductase
IPR006222 Glycine cleavage T-protein, N-terminal
IPR007375 Sarcosine oxidase, gamma subunit
IPR013977 Glycine cleavage T-protein, C-terminal barrel domain
IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain

PFAM

PF01266
PF01571
PF04268
PF08669

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DBT9

PhosphoSite