InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Usp16

Summary

InnateDB Protein

IDBP-173456.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Usp16

Protein Name

ubiquitin specific peptidase 16

Synonyms

1200004E02Rik; 2810483I07Rik; 6330514E22Rik; UBPM;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026710

InnateDB Gene

IDBG-173454 (Usp16)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0004197	cysteine-type endopeptidase activity
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0036459	ubiquitinyl hydrolase activity
GO:0042393	histone binding
GO:0043130	ubiquitin binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006508	proteolysis
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006974	cellular response to DNA damage stimulus
GO:0007067	mitotic nuclear division
GO:0016578	histone deubiquitination
GO:0035522	monoubiquitinated histone H2A deubiquitination
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045901	positive regulation of translational elongation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051289	protein homotetramerization
GO:0070537	histone H2A K63-linked deubiquitination

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1921362

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR001607 Zinc finger, UBP-type
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain

PFAM

PF00443
PF02148

PRINTS

PIRSF

SMART

SM00290

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99LG0