InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tbr1

Summary

InnateDB Protein

IDBP-173846.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tbr1

Protein Name

T-box brain gene 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000046787

InnateDB Gene

IDBG-173844 (Tbr1)

Protein Structure

UniProt Annotation

Function

Probable transcriptional regulator involved in developmental processes. Required for normal brain development.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00201}.

Disease Associations

Tissue Specificity

Expressed in specific lamina in the developing and adult brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007411	axon guidance
GO:0010092	specification of organ identity
GO:0010468	regulation of gene expression
GO:0010975	regulation of neuron projection development
GO:0030182	neuron differentiation
GO:0030902	hindbrain development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter