InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tbr1

Summary

InnateDB Protein

IDBP-173848.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Tbr1

Protein Name

T-box brain gene 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099798

InnateDB Gene

IDBG-173844 (Tbr1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007411	axon guidance
GO:0010092	specification of organ identity
GO:0010468	regulation of gene expression
GO:0010975	regulation of neuron projection development
GO:0030182	neuron differentiation
GO:0030902	hindbrain development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:107404

InterPro

IPR001699 Transcription factor, T-box
IPR008967 p53-like transcription factor, DNA-binding

PFAM

PF00907

PRINTS

PR00937

PIRSF

SMART

SM00425

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AR81

UniProt Splice Variant

Entrez Gene

21375

UniGene

Mm.404741

RefSeq

MGI ID

MGI Symbol

Tbr1

OMIM

CCDS

HPRD

IMGT

EMBL

AL845291

GenPept