InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Plk5

Summary

InnateDB Protein

IDBP-173884.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Plk5

Protein Name

polo-like kinase 5 (Drosophila)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000044400

InnateDB Gene

IDBG-173882 (Plk5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0002357	defense response to tumor cell
GO:0006468	protein phosphorylation
GO:0006927	transformed cell apoptotic process
GO:0010976	positive regulation of neuron projection development
GO:0031572	G2 DNA damage checkpoint
GO:0071363	cellular response to growth factor stimulus
GO:2000045	regulation of G1/S transition of mitotic cell cycle

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:3026984

InterPro

IPR000719 Protein kinase domain
IPR000959 POLO box duplicated domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF00659
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt