Version 5.4
Mus musculus Gene: Plk5
Summary
InnateDB Gene IDBG-173882.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plk5
Gene Name polo-like kinase 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035486
Encoded Proteins
IDBP-173884
polo-like kinase 5 (Drosophila)
IDBP-271061
polo-like kinase 5 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:80356459-80365489
Strand Forward strand
Band C1
Transcripts
ENSMUST00000039836 ENSMUSP00000044400
ENSMUST00000105351 ENSMUSP00000100988
ENSMUST00000152544
ENSMUST00000146826
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0046872 metal ion binding
Biological Process
GO:0002357 defense response to tumor cell
GO:0006468 protein phosphorylation
GO:0006927 transformed cell apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0008285 negative regulation of cell proliferation
GO:0010976 positive regulation of neuron projection development
GO:0031572 G2 DNA damage checkpoint
GO:0051301 cell division
GO:0071363 cellular response to growth factor stimulus
GO:2000045 regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.17613
RefSeq NM_183152 XM_006513499
OMIM
CCDS CCDS35980
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca