Version 5.4
Mus musculus Protein: Car14
Summary
InnateDB Protein IDBP-174117.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Car14
Protein Name carbonic anhydrase 14
Synonyms AW536446; Ca14;
Species Mus musculus
Ensembl Protein ENSMUSP00000036983
InnateDB Gene IDBG-174115 (Car14)
Protein Structure
UniProt Annotation
Function Reversible hydration of carbon dioxide.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Most abundant in the kidney and heart, followed by the skeletal muscle, brain, lung and liver.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0046872 metal ion binding
Biological Process
GO:0006885 regulation of pH
GO:0008152 metabolic process
GO:0015670 carbon dioxide transport
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1344341
InterPro IPR001148 Alpha carbonic anhydrase
PFAM PF00194
PRINTS
PIRSF
SMART SM01057
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WVT6
PhosphoSite PhosphoSite-Q9WVT6
TrEMBL
UniProt Splice Variant
Entrez Gene 23831
UniGene Mm.489647
RefSeq NP_035927
MGI ID 1RJ6
MGI Symbol Car14
OMIM
CCDS CCDS17625
HPRD
IMGT
EMBL AB005450 BC046995
GenPept AAH46995 BAA78709

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca