Mus musculus Gene: Car14
Summary
InnateDB Gene IDBG-174115.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Car14
Gene Name carbonic anhydrase 14
Synonyms AW536446; Ca14
Species Mus musculus
Ensembl Gene ENSMUSG00000038526
Encoded Proteins
carbonic anhydrase 14
carbonic anhydrase 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118298:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:95897768-95904691
Strand Reverse strand
Band F2.1
Transcripts
ENSMUST00000036181 ENSMUSP00000036983
ENSMUST00000147962 ENSMUSP00000117464
ENSMUST00000149202
ENSMUST00000126722
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0046872 metal ion binding
Biological Process
GO:0006885 regulation of pH
GO:0008152 metabolic process
GO:0015670 carbon dioxide transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Metabolism pathway
Reversible hydration of carbon dioxide pathway
KEGG
Nitrogen metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Reversible hydration of carbon dioxide pathway
Metabolism pathway
KEGG
Nitrogen metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9WVT6
TrEMBL D3Z4J8
UniProt Splice Variant
Entrez Gene 23831
UniGene Mm.489647
RefSeq NM_011797
OMIM
CCDS CCDS17625
HPRD
IMGT
MGI ID MGI:1344341
MGI Symbol Car14
EMBL AB005450 AC092855 BC046995
GenPept AAH46995 BAA78709
RNA Seq Atlas 23831