Version 5.4
Mus musculus Protein: Inf2
Summary
InnateDB Protein IDBP-174411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Inf2
Protein Name inverted formin, FH2 and WH2 domain containing
Synonyms 2610204M08Rik; AA589465; AW125550; EG629699;
Species Mus musculus
Ensembl Protein ENSMUSP00000098591
InnateDB Gene IDBG-174407 (Inf2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization
GO:0032535 regulation of cellular component size
GO:0090140 regulation of mitochondrial fission
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1917685
InterPro IPR003124 WH2 domain
IPR010472 Formin, FH3 domain
IPR010473 Formin, GTPase-binding domain
IPR015425 Formin, FH2 domain
IPR016024 Armadillo-type fold
PFAM PF02205
PF06367
PF06371
PF02181
PRINTS
PIRSF
SMART SM00246
SM00498
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9QLA5
UniProt Splice Variant
Entrez Gene 70435
UniGene Mm.250193
RefSeq NP_940803
MGI ID
MGI Symbol Inf2
OMIM
CCDS CCDS36571
HPRD
IMGT
EMBL AC124373
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca