InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Otud7b

Summary

InnateDB Protein

IDBP-174465.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Otud7b

Protein Name

OTU domain containing 7B

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096449

InnateDB Gene

IDBG-174459 (Otud7b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0005515	protein binding
GO:0008234	cysteine-type peptidase activity
GO:0008270	zinc ion binding
GO:0070530	K63-linked polyubiquitin binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0002385	mucosal immune response
GO:0006508	proteolysis
GO:0016579	protein deubiquitination
GO:0035871	protein K11-linked deubiquitination
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070536	protein K63-linked deubiquitination
GO:0071108	protein K48-linked deubiquitination