InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Col4a3bp

Summary

InnateDB Protein

IDBP-174714.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col4a3bp

Protein Name

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

Synonyms

2810404O15Rik; 9230101K08Rik; AU016711; CERT; GPBP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000076856

InnateDB Gene

IDBG-174712 (Col4a3bp)

Protein Structure

UniProt Annotation

Function

Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Note=Preferentially localized to the Golgi apparatus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0016301	kinase activity
GO:0035620	ceramide transporter activity
GO:0070273	phosphatidylinositol-4-phosphate binding
GO:0097001	ceramide binding

Biological Process

GO:0000902	cell morphogenesis
GO:0001701	in utero embryonic development
GO:0003007	heart morphogenesis
GO:0006672	ceramide metabolic process
GO:0006936	muscle contraction
GO:0007029	endoplasmic reticulum organization
GO:0007165	signal transduction
GO:0008283	cell proliferation
GO:0016310	phosphorylation
GO:0034976	response to endoplasmic reticulum stress
GO:0035621	ER to Golgi ceramide transport
GO:0055088	lipid homeostasis
GO:0070584	mitochondrion morphogenesis

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0048471	perinuclear region of cytoplasm