Version 5.4
Mus musculus Gene: Col4a3bp
Summary
InnateDB Gene IDBG-174712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Col4a3bp
Gene Name collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Synonyms 2810404O15Rik; 9230101K08Rik; AU016711; CERT; GPBP
Species Mus musculus
Ensembl Gene ENSMUSG00000021669
Encoded Proteins
IDBP-174714
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
IDBP-262381
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
IDBP-713268
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113163:
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:96542618-96640167
Strand Forward strand
Band D1
Transcripts
ENSMUST00000077672 ENSMUSP00000076856
ENSMUST00000109444 ENSMUSP00000105070
ENSMUST00000179226 ENSMUSP00000136766
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0016301 kinase activity
GO:0035620 ceramide transporter activity
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0097001 ceramide binding
Biological Process
GO:0000902 cell morphogenesis
GO:0001701 in utero embryonic development
GO:0003007 heart morphogenesis
GO:0006672 ceramide metabolic process
GO:0006936 muscle contraction
GO:0007029 endoplasmic reticulum organization
GO:0007165 signal transduction
GO:0008283 cell proliferation
GO:0016310 phosphorylation
GO:0034976 response to endoplasmic reticulum stress
GO:0035621 ER to Golgi ceramide transport
GO:0055088 lipid homeostasis
GO:0070584 mitochondrion morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113163
View Gene Order
ENSBTAG00000000081
Not yet available
Pathways
NETPATH
REACTOME
REACT_198151
Sphingolipid de novo biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_204257
Sphingolipid de novo biosynthesis pathway
REACT_222556
Sphingolipid metabolism pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.24125 Mm.416013
RefSeq NM_001164222 NM_023420
OMIM
CCDS CCDS26705 CCDS49335
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca