Version 5.4
Mus musculus Protein: Col17a1
Summary
InnateDB Protein IDBP-174967.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Col17a1
Protein Name collagen, type XVII, alpha 1
Synonyms BP180; Bpag; Bpag2;
Species Mus musculus
Ensembl Protein ENSMUSP00000026045
InnateDB Gene IDBG-174965 (Col17a1)
Protein Structure
UniProt Annotation
Function May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. {ECO:0000250}.The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion. {ECO:0000250}.
Subcellular Localization Cell junction, hemidesmosome. Membrane; Single-pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome. {ECO:0000250}.120 kDa linear IgA disease antigen homolog: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0031581 hemidesmosome assembly
Cellular Component
GO:0005581 collagen trimer
GO:0005604 basement membrane
GO:0016021 integral component of membrane
GO:0030056 hemidesmosome
Protein Structure and Domains
PDB ID MGI:88450
InterPro IPR008160 Collagen triple helix repeat
PFAM PF01391
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q07563
PhosphoSite PhosphoSite-Q07563
TrEMBL
UniProt Splice Variant
Entrez Gene 12821
UniGene Mm.398547
RefSeq NP_001277754
MGI ID
MGI Symbol Col17a1
OMIM
CCDS CCDS70959
HPRD
IMGT
EMBL AC131719 AK135150 BC003208 BC125031 BC125032 L08407
GenPept AAA37443 AAH03208 AAI25032 AAI25033 BAE22442

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca