Version 5.4
Homo sapiens Protein: SCT
Summary
InnateDB Protein IDBP-17497.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCT
Protein Name secretin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000176195
InnateDB Gene IDBG-17495 (SCT)
Protein Structure
UniProt Annotation
Function Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0008542 visual learning
GO:0021542 dentate gyrus development
GO:0030157 pancreatic juice secretion
GO:0043524 negative regulation of neuron apoptotic process
GO:0097150 neuronal stem cell maintenance
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000532 Glucagon/GIP/secretin/VIP
PFAM PF00123
PRINTS PR00275
PIRSF
SMART SM00070
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09683
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 6343
UniGene Hs.632324
RefSeq NP_068739
HUGO HGNC:10607
OMIM 182099
CCDS CCDS7709
HPRD 08354
IMGT
EMBL AF244355
GenPept AAG31443

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca